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Liz Morris

POSTDOCTORAL TRAINING FELLOW

Crystal structure of the Trim5α HIV-1 restriction factor.

Taylor lab

Macromolecular Structure Laboratory

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Last updated : 07 June 2023 02:22

Probing the catalytic mechanism and inhibition of SAMHD1 using the differential properties of Rp- and Sp-dNTPαS diastereomers

Authors (6)

Published 1 June 2021

Crick labs/ facilities

Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis

Authors (7)

Liz Morris
Sarah Caswell
Simone Kunzelmann
Laurence H Arnold
Andrew G Purkiss
Geoff Kelly
Ian Taylor

Nature Communications

Published 23 June 2020

Crick labs/ facilities

Positive selection in dNTPase SAMHD1 throughout mammalian evolution

Authors (12)

Christopher Monit
Liz Morris
Christopher Ruis
Bart Szafran
Grant Thiltgen
Chloe Tsai
[...]
Kate Bishop
Jonathan Stoye
Ian Taylor
Ariberto Fassati
Richard A Goldstein

Proceedings of the National Academy of Sciences of the United States of America

Published 10 September 2019

Crick labs