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Breadcrumb Research A Z researchers Matthew Cockman SENIOR LABORATORY RESEARCH SCIENTIST Ratcliffe lab Hypoxia Biology Laboratory Email Address: Email Phone Number: +44 (0)20 3796 3488 Year published2021 (1)2019 (2)2018 (1)2017 (1)2014 (4)2012 (2) Facet Year publishedResearch topicsBiochemistry & Proteomics (4)Cell Biology (4)Metabolism (4)Signalling & Oncogenes (4) Facet Research topicsPublication typeJournal article (11)Primary research (11) Facet Publication typeJournalAmerican Journal of Human Genetics (1)Cardiovascular Research (1)eLife (1)EMBO Reports (1)Journal of Proteomics & Bioinformatics (1)Molecular Cell (1)Nature Chemical Biology (2)Proceedings of the National Academy of Sciences of the United States of America (3) Facet JournalCrick Pre-CrickCrick publications (4)Pre-Crick publications (7) Facet Crick Pre-Crick Displaying 1 - 11 of 11Last updated : 06 February 2023 03:15 Ogfod1 deletion increases cardiac beta-alanine levels and protects mice against ischemia-reperfusion injury Authors (11) Michael Harris Junhui Sun Karen Keeran Angel Aponte Komudi Singh Danielle Springer Marjan Gucek Mehdi PiroozniaMatthew Cockman Elizabeth Murphy Leslie M Kennedy Cardiovascular Research Published 20 October 2021 Crick labsPeter RatcliffeFull details Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates Authors (11)Matthew Cockman Kerstin Lippl Ya-Min TianHamish Pegg William D Figg Martine I Abboud Raphael Heilig Roman Fischer Johanna Myllyharju Christopher J SchofieldPeter Ratcliffe eLife Published 10 September 2019 Crick labs/ facilitiesPeter RatcliffeProteomicsPeptide ChemistryFull details Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin Authors (11) James A Smythies Min Sun Norma Masson Rafik Salama Peter D Simpson Elizabeth Murray Viviana NeumannMatthew Cockman Hani ChoudhryPeter Ratcliffe David R Mole EMBO Reports Published 1 January 2019 Crick labsPeter RatcliffeFull details The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases Authors (23) Suzana Markolovic Qinqin Zhuang Sarah E Wilkins Charlotte D Eaton Martine I Abboud Maximiliano J Katz[...] Roman Fischer Pablo Wappner Rasheduzzaman Chowdhury Mathew L Coleman Christopher J Schofield Nature Chemical Biology Published 18 June 2018 Crick labsKaren VousdenPeter RatcliffeFull details A ribosomopathy reveals decoding defective ribosomes driving human dysmorphism Authors (20) Nahuel A Paolini Martin Attwood Samuel B Sondalle Carolina Marques Dos Santos Vieira Anita M van Adrichem Franca M di Summa[...] Taco W Kuijpers Jonathan D Dinman Susan J BasergaMatthew Cockman Alyson W MacInnes American Journal of Human Genetics Published 2 March 2017 Crick labsPeter RatcliffeFull details Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy Authors (12) Christoph Loenarz Rok Sekirnik Armin Thalhammer Wei Ge Ekaterina Spivakovsky Mukram M Mackeen[...]Matthew Cockman Benedikt M KesslerPeter Ratcliffe Alexander Wolf Christopher J Schofield Proceedings of the National Academy of Sciences of the United States of America Published 18 March 2014 Crick labsPeter RatcliffeFull details OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation Authors (19) Rachelle S Singleton Phebee Liu-Yi Fabio Formenti Wei Ge Rok Sekirnik Roman Fischer[...] Benedikt M Kessler Pablo Wappner Christopher J SchofieldPeter RatcliffeMatthew Cockman Proceedings of the National Academy of Sciences of the United States of America Published 18 March 2014 Crick labsPeter RatcliffeFull details Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth Authors (17) Maximiliano J Katz Julieta M Acevedo Christoph Loenarz Diego Galagovsky Phebee Liu-Yi Marcelo Pérez-Pepe[...] Graciela L Boccaccio Christopher J SchofieldMatthew CockmanPeter Ratcliffe Pablo Wappner Proceedings of the National Academy of Sciences of the United States of America Published 18 March 2014 Crick labsPeter RatcliffeFull details Optimal translational termination requires C4 lysyl hydroxylation of eRF1 Authors (22) Tianshu Feng Atsushi Yamamoto Sarah E Wilkins Elizaveta Sokolova Luke A Yates Martin Münzel[...] Ludmila Y Frolova Elena AlkalaevaPeter Ratcliffe Christopher J Schofield Mathew L Coleman Molecular Cell Published 20 February 2014 Crick labsPeter RatcliffeFull details Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans Authors (32) Wei Ge Alexander Wolf Tianshu Feng Chia-hua Ho Rok Sekirnik Adam Zayer[...] Benedikt M KesslerPeter Ratcliffe Gail M Preston Mathew L Coleman Christopher J Schofield Nature Chemical Biology Published 1 December 2012 Crick labsPeter RatcliffeFull details ModLS: post-translational modification localization scoring with automatic specificity expansion Authors (5) David C Trudgian Rachelle SingletonMatthew CockmanPeter Ratcliffe Benedikt M Kessler Journal of Proteomics & Bioinformatics Published 1 January 2012 Crick labsPeter RatcliffeFull details
Ogfod1 deletion increases cardiac beta-alanine levels and protects mice against ischemia-reperfusion injury Authors (11) Michael Harris Junhui Sun Karen Keeran Angel Aponte Komudi Singh Danielle Springer Marjan Gucek Mehdi PiroozniaMatthew Cockman Elizabeth Murphy Leslie M Kennedy Cardiovascular Research Published 20 October 2021 Crick labsPeter RatcliffeFull details
Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates Authors (11)Matthew Cockman Kerstin Lippl Ya-Min TianHamish Pegg William D Figg Martine I Abboud Raphael Heilig Roman Fischer Johanna Myllyharju Christopher J SchofieldPeter Ratcliffe eLife Published 10 September 2019 Crick labs/ facilitiesPeter RatcliffeProteomicsPeptide ChemistryFull details
Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin Authors (11) James A Smythies Min Sun Norma Masson Rafik Salama Peter D Simpson Elizabeth Murray Viviana NeumannMatthew Cockman Hani ChoudhryPeter Ratcliffe David R Mole EMBO Reports Published 1 January 2019 Crick labsPeter RatcliffeFull details
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases Authors (23) Suzana Markolovic Qinqin Zhuang Sarah E Wilkins Charlotte D Eaton Martine I Abboud Maximiliano J Katz[...] Roman Fischer Pablo Wappner Rasheduzzaman Chowdhury Mathew L Coleman Christopher J Schofield Nature Chemical Biology Published 18 June 2018 Crick labsKaren VousdenPeter RatcliffeFull details
A ribosomopathy reveals decoding defective ribosomes driving human dysmorphism Authors (20) Nahuel A Paolini Martin Attwood Samuel B Sondalle Carolina Marques Dos Santos Vieira Anita M van Adrichem Franca M di Summa[...] Taco W Kuijpers Jonathan D Dinman Susan J BasergaMatthew Cockman Alyson W MacInnes American Journal of Human Genetics Published 2 March 2017 Crick labsPeter RatcliffeFull details
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy Authors (12) Christoph Loenarz Rok Sekirnik Armin Thalhammer Wei Ge Ekaterina Spivakovsky Mukram M Mackeen[...]Matthew Cockman Benedikt M KesslerPeter Ratcliffe Alexander Wolf Christopher J Schofield Proceedings of the National Academy of Sciences of the United States of America Published 18 March 2014 Crick labsPeter RatcliffeFull details
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation Authors (19) Rachelle S Singleton Phebee Liu-Yi Fabio Formenti Wei Ge Rok Sekirnik Roman Fischer[...] Benedikt M Kessler Pablo Wappner Christopher J SchofieldPeter RatcliffeMatthew Cockman Proceedings of the National Academy of Sciences of the United States of America Published 18 March 2014 Crick labsPeter RatcliffeFull details
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth Authors (17) Maximiliano J Katz Julieta M Acevedo Christoph Loenarz Diego Galagovsky Phebee Liu-Yi Marcelo Pérez-Pepe[...] Graciela L Boccaccio Christopher J SchofieldMatthew CockmanPeter Ratcliffe Pablo Wappner Proceedings of the National Academy of Sciences of the United States of America Published 18 March 2014 Crick labsPeter RatcliffeFull details
Optimal translational termination requires C4 lysyl hydroxylation of eRF1 Authors (22) Tianshu Feng Atsushi Yamamoto Sarah E Wilkins Elizaveta Sokolova Luke A Yates Martin Münzel[...] Ludmila Y Frolova Elena AlkalaevaPeter Ratcliffe Christopher J Schofield Mathew L Coleman Molecular Cell Published 20 February 2014 Crick labsPeter RatcliffeFull details
Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans Authors (32) Wei Ge Alexander Wolf Tianshu Feng Chia-hua Ho Rok Sekirnik Adam Zayer[...] Benedikt M KesslerPeter Ratcliffe Gail M Preston Mathew L Coleman Christopher J Schofield Nature Chemical Biology Published 1 December 2012 Crick labsPeter RatcliffeFull details
ModLS: post-translational modification localization scoring with automatic specificity expansion Authors (5) David C Trudgian Rachelle SingletonMatthew CockmanPeter Ratcliffe Benedikt M Kessler Journal of Proteomics & Bioinformatics Published 1 January 2012 Crick labsPeter RatcliffeFull details
