Minee Choi

GROUP MEMBER - SECONDMENT

Dopaminergic neurons generated from human induced pluripotent stem cells. Blue stain for the nuclei and yellow stain for tyrosine hydroxylase, a dopaminergic neuron marker.

Gandhi lab

Neurodegeneration Biology Laboratory

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Displaying 1 - 10 of 10

Last updated : 06 February 2023 03:52

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Authors (19)

Plamena R Angelova
Minee Choi
Alexey V Berezhnov
Mathew H Horrocks
Craig D Hughes
Suman De
[...]
Sergiy Sylantyev
Evgeny V Pavlov
David Klenerman
Andrey Y Abramov
Sonia Gandhi

Cell Death and Differentiation

Published 1 October 2020

Crick labs

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Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death

Authors (10)

Craig Hughes
Minee Choi
Jee-Hyun Yi
Seung-Chan Kim
Anna Drews
Peter St George-Hyslop
Clare Bryant
Sonia Gandhi
Kwangwook Cho
David Klenerman

Communications Biology

Published 18 February 2020

Crick labs

Sonia Gandhi

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Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson's disease pathogenesis

Authors (12)

Craig D Hughes
Minee Choi
Mina Ryten
Lee Hopkins
Anna Drews
Juan A Botía
[...]
Margarida Rodrigues
Sarah A Gagliano
Sonia Gandhi
Clare Bryant
David Klenerman

Acta Neuropathologica

Published 1 January 2019

Crick labs

Sonia Gandhi

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Nanoscopic characterisation of individual endogenous protein aggregates in human neuronal cells

Authors (17)

Daniel R Whiten
Yukun Zuo
Laura Calo
Minee Choi
Suman De
Patrick Flagmeier
[...]
Christopher M Dobson
Sonia Gandhi
Maria-Grazia Spillantini
David Klenerman
Mathew H Horrocks

ChemBioChem: a European journal of chemical biology

Published 4 October 2018

Crick labs

Sonia Gandhi

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Crucial role of protein oligomerization in the pathogenesis of Alzheimer's and Parkinson's diseases

Authors (2)

FEBS Journal

Published 1 October 2018

Crick labs

Sonia Gandhi

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α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

Authors (23)

Marthe HR Ludtmann
Plamena R Angelova
Mathew H Horrocks
Minee Choi
Margarida Rodrigues
Artyom Y Baev
[...]
Morana Jaganjac
Evgeny V Pavlov
David Klenerman
Andrey Y Abramov
Sonia Gandhi

Nature Communications

Published 12 June 2018

Crick labs

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Nanobodies raised against monomeric α-synuclein inhibit fibril formation and destabilize toxic oligomeric species

Authors (18)

Marija Iljina
Liu Hong
Mathew H Horrocks
Marthe H Ludtmann
Minee Choi
Craig D Hughes
[...]
Michele Vendruscolo
Tuomas PJ Knowles
Christopher M Dobson
Erwin De Genst
David Klenerman

BMC Biology

Published 3 July 2017

Crick labs

Sonia Gandhi

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Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS

Authors (24)

Claire E Hall
Zhi Yao
Minee Choi
Giulia E Tyzack
Andrea Serio
Raphaelle Luisier
[...]
Christopher R Sibley
Andras Lakatos
Jernej Ule
Sonia Gandhi
Rickie Patani

Cell Reports

Published 30 May 2017

Crick labs

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Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein

Authors (9)

Marija Iljina
Laura Tosatto
Minee Choi
Jason C Sang
Yu Ye
Craig D Hughes
Clare E Bryant
Sonia Gandhi
David Klenerman

Scientific Reports

Published 27 September 2016

Crick labs

Sonia Gandhi

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Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading

Authors (13)

Marija Iljina
Gonzalo A Garcia
Mathew H Horrocks
Laura Tosatto
Minee Choi
Kristina A Ganzinger
[...]
Nicholas W Wood
Nunilo Cremades
Christopher M Dobson
Tuomas PJ Knowles
David Klenerman

Proceedings of the National Academy of Sciences of the United States of America

Published 1 March 2016

Crick labs

Sonia Gandhi

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Coronavirus (COVID-19) response

Vacancies

Outwitting Cancer

Coronavirus (COVID-19) research

About us

Minee Choi

GROUP MEMBER - SECONDMENT

Gandhi lab

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Crick Pre-Crick

Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation

Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and rat neuronal cell death

Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson's disease pathogenesis

Nanoscopic characterisation of individual endogenous protein aggregates in human neuronal cells

Crucial role of protein oligomerization in the pathogenesis of Alzheimer's and Parkinson's diseases

α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson’s disease

Nanobodies raised against monomeric α-synuclein inhibit fibril formation and destabilize toxic oligomeric species

Progressive motor neuron pathology and the role of astrocytes in a human stem cell model of VCP-related ALS

Arachidonic acid mediates the formation of abundant alpha-helical multimers of alpha-synuclein

Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading

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