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Breadcrumb David LV Bauer Bauer lab RNA Virus Replication Laboratory : Publications Lab contentLab contentIn this section Overview Lab members Areas of interest Vacancies Publications Publications Displaying 1 - 20 of 20Last updated : 01 April 2023 02:23 Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer Authors (62)Annika FendlerScott ShepherdLewis AuMary Wu Ruth Harvey Andreas M Schmitt[...] Emma Nicholson Susanna Walker James LarkinSamra Turajlic The CAPTURE consortium The Lancet Published 25 January 2022 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyMetabolomicsHigh Throughput ScreeningBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Omicron neutralising antibodies after COVID-19 vaccination in haemodialysis patients Authors (19) Edward J CarrMary Wu Ruth Harvey Roseanne E Billany Emma C WallGavin Kelly[...] Rachel B Jones Rona M Smith Stephen McAdoo Michelle WillicombeRupert Beale The Lancet Published 20 January 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreHigh Throughput ScreeningBioinformatics and BiostatisticsFull details Three-dose vaccination elicits neutralising antibodies against omicron Authors (26)Mary Wu Emma C Wall Edward J Carr Ruth Harvey Hermaleigh TownsleyHarriet Mears[...] Vincenzo Libri Bryan WilliamsSonia GandhiCharles SwantonDavid LV Bauer The Lancet Published 19 January 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer Authors (65)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary Wu Andreas M Schmitt[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic CAPTURE consortium Cancer Cell Published 29 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyProteomicsMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Real-time single-molecule studies of RNA polymerase-promoter open complex formation reveal substantial heterogeneity along the promoter-opening pathway Authors (9) Anssi M Malinen Jacob Bakermans Emil Aalto-Setälä Martin BlessingDavid LV Bauer Olena Parilova Georgiy A Belogurov David Dulin Achillefs N Kapanidis Journal of Molecular Biology Published 30 January 2022 Crick labsDavid LV BauerFull details Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study Authors (98)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary WuFiona Byrne[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic CAPTURE Consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study Authors (98)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary WuFiona Byrne[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic The CAPTURE Consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients Authors (86) Edward J Carr Mary Wu Ruth Harvey Emma C WallGavin KellySaira Hussain[...]Emma RussellAndy RiddellSvend KjaerAnnabel BorgChloe Roustan The Lancet Published 18 September 2021 Crick labs/ facilitiesCharles SwantonGitta StockingerJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyPeptide ChemistryHigh Throughput ScreeningFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsScientific computingAdvanced SequencingFull details Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains Authors (30)Nikhil FaulknerKevin NgMary Wu Ruth Harvey Marios Margaritis Stavroula Paraskevopoulou[...]Michael HowellDavid LV Bauer Eleni Nastouli SAFER InvestigatorsGeorge Kassiotis eLife Published 29 July 2021 Crick labs/ facilitiesCharles SwantonGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningFlow CytometryCell ServicesFull details Structure of an H3N2 influenza virus nucleoprotein Authors (6) Michael L Knight Haitian FanDavid LV Bauer Jonathan M Grimes Ervin Fodor Jeremy R Keown Acta Crystallographica Section F: Structural Biology Communications Published 1 July 2021 Crick labsDavid LV BauerFull details A synergistic effect between 3′ -terminal noncoding and adjacent coding regions of influenza A virus hemagglutinin segment on template preference Authors (8) Yue Xiao Wenyu Zhang Minglei PanDavid LV Bauer Yuhai Bi Mengmeng Cao Ervin Fodor Tao Deng Journal of Virology Published 25 August 2021 Crick labsDavid LV BauerFull details AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC Authors (24) Emma C WallMary Wu Ruth HarveyGavin Kelly Scott WarchalChelsea Sawyer[...] Vincenzo Libri Bryan WilliamsCharles SwantonSonia GandhiDavid LV Bauer Lancet Published 17 July 2021 Crick labs/ facilitiesCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsScientific computingFull details Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination Authors (25) Emma C WallMary Wu Ruth HarveyGavin Kelly Scott WarchalChelsea Sawyer[...] Vincenzo Libri Bryan WilliamsCharles SwantonSonia GandhiDavid LV Bauer The Lancet Published 19 June 2021 Crick labs/ facilitiesCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details The structure of the influenza A virus genome Authors (9) Bernadeta Dadonaite Brad Gilbertson Michael L Knight Sanja Trifkovic Steven Rockman Alain Laederach Lorena E Brown Ervin FodorDavid LV Bauer Nature Microbiology Published 22 July 2019 Crick labsDavid LV BauerFull details Mini viral RNAs act as innate immune agonists during influenza virus infection Authors (15) Aartjan JW te Velthuis Joshua C LongDavid LV Bauer Rebecca LY Fan Hui-Ling Yen Jane Sharps[...] Richard E Randall Emmie de Wit Debby van Riel Leo LM Poon Ervin Fodor Nature Microbiology Published 1 November 2018 Crick labsDavid LV BauerFull details Influenza virus mounts a two-pronged attack on host RNA polymerase II transcription Authors (7)David LV Bauer Michael Tellier Mónica Martínez-Alonso Takayuki Nojima Nick J Proudfoot Shona Murphy Ervin Fodor Cell Reports Published 15 May 2018 Crick labsDavid LV BauerFull details Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria Authors (11) David DulinDavid LV Bauer Anssi M Malinen Jacob JW Bakermans Martin Kaller Zakia Morichaud Ivan Petushkov Martin Depken Konstantin Brodolin Andrey Kulbachinskiy Achillefs N Kapanidis Nature Communications Published 16 April 2018 Crick labsDavid LV BauerFull details Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity Authors (6) Joshua D Eaton Lee DavidsonDavid LV Bauer Toyoaki Natsume Masato T Kanemaki Steven West Genes and Development Published 15 January 2018 Crick labsDavid LV BauerFull details RNA polymerase pausing during initial transcription Authors (12) Diego DuchiDavid LV Bauer Laurent Fernandez Geraint Evans Nicole Robb Ling Chin Hwang[...] Alexandra Tomescu Pawel Zawadzki Zakia Morichaud Konstantin Brodolin Achillefs N Kapanidis Molecular Cell Published 15 September 2016 Crick labsDavid LV BauerFull details New technologies for DNA analysis - a review of the READNA Project Authors (67) Steven McGinnDavid LV Bauer Thomas Brefort Liqin Dong Afaf El-Sagheer Abdou Elsharawy[...] Anthony J Brookes Kalim Mir Mats Nilsson James P Willcocks Ivo G Gut New Biotechnology Published 25 May 2016 Crick labsDavid LV BauerFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Omicron neutralising antibodies after third COVID-19 vaccine dose in patients with cancer Authors (62)Annika FendlerScott ShepherdLewis AuMary Wu Ruth Harvey Andreas M Schmitt[...] Emma Nicholson Susanna Walker James LarkinSamra Turajlic The CAPTURE consortium The Lancet Published 25 January 2022 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyMetabolomicsHigh Throughput ScreeningBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Omicron neutralising antibodies after COVID-19 vaccination in haemodialysis patients Authors (19) Edward J CarrMary Wu Ruth Harvey Roseanne E Billany Emma C WallGavin Kelly[...] Rachel B Jones Rona M Smith Stephen McAdoo Michelle WillicombeRupert Beale The Lancet Published 20 January 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreHigh Throughput ScreeningBioinformatics and BiostatisticsFull details
Three-dose vaccination elicits neutralising antibodies against omicron Authors (26)Mary Wu Emma C Wall Edward J Carr Ruth Harvey Hermaleigh TownsleyHarriet Mears[...] Vincenzo Libri Bryan WilliamsSonia GandhiCharles SwantonDavid LV Bauer The Lancet Published 19 January 2022 Crick labs/ facilitiesCharles SwantonGitta StockingerJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningBioinformatics and BiostatisticsScientific computingFull details
Immune responses following third COVID-19 vaccination are reduced in patients with hematological malignancies compared to patients with solid cancer Authors (65)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary Wu Andreas M Schmitt[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic CAPTURE consortium Cancer Cell Published 29 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyProteomicsMetabolomicsHigh Throughput ScreeningBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Real-time single-molecule studies of RNA polymerase-promoter open complex formation reveal substantial heterogeneity along the promoter-opening pathway Authors (9) Anssi M Malinen Jacob Bakermans Emil Aalto-Setälä Martin BlessingDavid LV Bauer Olena Parilova Georgiy A Belogurov David Dulin Achillefs N Kapanidis Journal of Molecular Biology Published 30 January 2022 Crick labsDavid LV BauerFull details
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study Authors (98)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary WuFiona Byrne[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic CAPTURE Consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study Authors (98)Annika FendlerScott ShepherdLewis AuKatalin WilkinsonMary WuFiona Byrne[...] Susanna WalkerRobert Wilkinson James LarkinSamra Turajlic The CAPTURE Consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinDavid LV BauerWorldwide Influenza CentreMetabolomicsHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients Authors (86) Edward J Carr Mary Wu Ruth Harvey Emma C WallGavin KellySaira Hussain[...]Emma RussellAndy RiddellSvend KjaerAnnabel BorgChloe Roustan The Lancet Published 18 September 2021 Crick labs/ facilitiesCharles SwantonGitta StockingerJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyPeptide ChemistryHigh Throughput ScreeningFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsScientific computingAdvanced SequencingFull details
Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains Authors (30)Nikhil FaulknerKevin NgMary Wu Ruth Harvey Marios Margaritis Stavroula Paraskevopoulou[...]Michael HowellDavid LV Bauer Eleni Nastouli SAFER InvestigatorsGeorge Kassiotis eLife Published 29 July 2021 Crick labs/ facilitiesCharles SwantonGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyHigh Throughput ScreeningFlow CytometryCell ServicesFull details
Structure of an H3N2 influenza virus nucleoprotein Authors (6) Michael L Knight Haitian FanDavid LV Bauer Jonathan M Grimes Ervin Fodor Jeremy R Keown Acta Crystallographica Section F: Structural Biology Communications Published 1 July 2021 Crick labsDavid LV BauerFull details
A synergistic effect between 3′ -terminal noncoding and adjacent coding regions of influenza A virus hemagglutinin segment on template preference Authors (8) Yue Xiao Wenyu Zhang Minglei PanDavid LV Bauer Yuhai Bi Mengmeng Cao Ervin Fodor Tao Deng Journal of Virology Published 25 August 2021 Crick labsDavid LV BauerFull details
AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC Authors (24) Emma C WallMary Wu Ruth HarveyGavin Kelly Scott WarchalChelsea Sawyer[...] Vincenzo Libri Bryan WilliamsCharles SwantonSonia GandhiDavid LV Bauer Lancet Published 17 July 2021 Crick labs/ facilitiesCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsScientific computingFull details
Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination Authors (25) Emma C WallMary Wu Ruth HarveyGavin Kelly Scott WarchalChelsea Sawyer[...] Vincenzo Libri Bryan WilliamsCharles SwantonSonia GandhiDavid LV Bauer The Lancet Published 19 June 2021 Crick labs/ facilitiesCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreHigh Throughput ScreeningFlow CytometryBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
The structure of the influenza A virus genome Authors (9) Bernadeta Dadonaite Brad Gilbertson Michael L Knight Sanja Trifkovic Steven Rockman Alain Laederach Lorena E Brown Ervin FodorDavid LV Bauer Nature Microbiology Published 22 July 2019 Crick labsDavid LV BauerFull details
Mini viral RNAs act as innate immune agonists during influenza virus infection Authors (15) Aartjan JW te Velthuis Joshua C LongDavid LV Bauer Rebecca LY Fan Hui-Ling Yen Jane Sharps[...] Richard E Randall Emmie de Wit Debby van Riel Leo LM Poon Ervin Fodor Nature Microbiology Published 1 November 2018 Crick labsDavid LV BauerFull details
Influenza virus mounts a two-pronged attack on host RNA polymerase II transcription Authors (7)David LV Bauer Michael Tellier Mónica Martínez-Alonso Takayuki Nojima Nick J Proudfoot Shona Murphy Ervin Fodor Cell Reports Published 15 May 2018 Crick labsDavid LV BauerFull details
Pausing controls branching between productive and non-productive pathways during initial transcription in bacteria Authors (11) David DulinDavid LV Bauer Anssi M Malinen Jacob JW Bakermans Martin Kaller Zakia Morichaud Ivan Petushkov Martin Depken Konstantin Brodolin Andrey Kulbachinskiy Achillefs N Kapanidis Nature Communications Published 16 April 2018 Crick labsDavid LV BauerFull details
Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity Authors (6) Joshua D Eaton Lee DavidsonDavid LV Bauer Toyoaki Natsume Masato T Kanemaki Steven West Genes and Development Published 15 January 2018 Crick labsDavid LV BauerFull details
RNA polymerase pausing during initial transcription Authors (12) Diego DuchiDavid LV Bauer Laurent Fernandez Geraint Evans Nicole Robb Ling Chin Hwang[...] Alexandra Tomescu Pawel Zawadzki Zakia Morichaud Konstantin Brodolin Achillefs N Kapanidis Molecular Cell Published 15 September 2016 Crick labsDavid LV BauerFull details
New technologies for DNA analysis - a review of the READNA Project Authors (67) Steven McGinnDavid LV Bauer Thomas Brefort Liqin Dong Afaf El-Sagheer Abdou Elsharawy[...] Anthony J Brookes Kalim Mir Mats Nilsson James P Willcocks Ivo G Gut New Biotechnology Published 25 May 2016 Crick labsDavid LV BauerFull details
