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Breadcrumb Dinis Calado Calado lab Immunity & Cancer Laboratory : Publications Lab contentLab contentIn this section Overview Vacancies Areas of interest Publications Germinal center B cells (red), naïve B cells (purple) and macrophages (green) in a spleen tissue section. Credit: Giulia Morlino. Toggle to view hero caption Publications Displaying 1 - 20 of 21Last updated : 29 May 2023 02:43 Generation and surgical analysis of genetic mouse models to study NF-κB-driven pathogenesis of Diffuse Large B Cell Lymphoma Authors (5) Bernard D Maybury Yolanda Saavedra-TorresThomas Snoeks Jude FitzgibbonDinis Calado Methods in Molecular Biology Published 9 July 2021 Crick labs/ facilitiesDinis CaladoIn Vivo ImagingBiological Research FacilityFull details Immune crosstalk between lymph nodes and breast carcinomas, with a focus on B cells Authors (4) Elena Alberts Isobelle WallDinis Calado Anita Grigoriadis Frontiers in Molecular Biosciences Published 1 May 2021 Crick labsDinis CaladoFull details Positive selection in the light zone of germinal centers Authors (2)Rinako NakagawaDinis Calado Frontiers in Immunology Published 1 March 2021 Crick labsDinis CaladoFull details Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth Authors (11)Rinako Nakagawa Amparo Toboso-Navasa Marta SchipsGeorge Young Leena Bhaw-Rosun Miriam Llorian-Sopena Probir Chakravarty Abdul Karim SesayGeorge Kassiotis Michael Meyer-HermannDinis Calado Proceedings of the National Academy of Sciences of USA Published 12 January 2021 Crick labs/ facilitiesGeorge KassiotisDinis CaladoBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityFull details Genetic timestamping of plasma cells in vivo reveals tissue-specific homeostatic population turnover Authors (3) An Qi Xu Rita R BarbosaDinis Calado eLife Published 2 November 2020 Crick labs/ facilitiesDinis CaladoFlow CytometryBiological Research FacilityFull details Restriction of memory B cell differentiation at the germinal center B cell positive selection stage Authors (13) Amparo Toboso-Navasa Arief Gunawan Giulia MorlinoRinako Nakagawa Andrea Taddei Djamil Damry[...] Martin JanzGeorge Kassiotis Robert Brink Martin EilersDinis Calado Journal of Experimental Medicine Published 6 July 2020 Crick labs/ facilitiesGeorge KassiotisDinis CaladoBioinformatics and BiostatisticsLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details RAC1P29S induces a mesenchymal phenotypic switch via serum response factor to promote melanoma development and therapy resistance Authors (17) Daniël A LionaronsDavid HancockSareena Rana Philip EastChristopher MooreMiguel Murillo[...]Ian Rosewell Ralph Fritsch Richard NeubigMiriam Molina ArcasJulian Downward Cancer Cell Published 8 July 2019 Crick labs/ facilitiesJulian DownwardDinis CaladoGenetic Modification ServiceExperimental HistopathologyBiological Research FacilityBioinformatics and BiostatisticsFull details Validation and invalidation of chemical probes for the human N-myristoyltransferases Authors (9) Wouter W Kallemeijn Gregor A Lueg Monica Faronato Kate Hadavizadeh Andrea Goya Grocin Ok-Ryul SongMichael HowellDinis Calado Edward W Tate Cell Chemical Biology Published 20 June 2019 Crick labs/ facilitiesEd TateDinis CaladoHigh Throughput ScreeningCell ServicesFull details MicroRNA-155 protects group 2 innate lymphoid cells from apoptosis to promote type-2 immunity Authors (8) Martin D Knolle Shau Bing Chin Batika MJ Rana Alexandros EnglezakisRinako Nakagawa Padraic G Fallon Anna Git Andrew NJ McKenzie Frontiers in Immunology Published 9 October 2018 Crick labsDinis CaladoFull details Restoration of endogenous retrovirus infectivity impacts mouse cancer models Authors (10)Eleonora Ottina Prisca LevyUrszula Eksmond Julia MerkenschlagerGeorge Young Juliette RoelsJonathan Stoye Thomas TütingDinis CaladoGeorge Kassiotis Cancer Immunology Research Published 1 November 2018 Crick labs/ facilitiesJonathan StoyeGeorge KassiotisDinis CaladoFlow CytometryBiological Research FacilityFull details BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma Authors (20) Kyren A Lazarus Fazal Hadi Elisabetta Zambon Karsten Bach Maria-Francesca Santolla Julie K Watson[...] Frank M McCaughan John Le Quesne Joo-Hyeon LeeDinis Calado Walid T Khaled Nature Communications Published 20 August 2018 Crick labsDinis CaladoFull details Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program Authors (14) Maike Frye Andrea Taddei Cathrin Dierkes Ines Martinez-Corral Matthew Fielden Henrik Ortsäter[...] Marjo Salminen Liqun He Natasha L Harvey Friedemann Kiefer Taija Mäkinen Nature Communications Published 17 April 2018 Crick labs/ facilitiesDinis CaladoFlow CytometryFull details FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy Authors (19) Beata Pyrzynska Michal Dwojak Abdessamad Zerrouqi Giulia Morlino Piotr Zapala Nina Miazek[...] Dimitar G Efremov Przemyslaw JuszczynskiDinis Calado Jakub Golab Magdalena Winiarska Oncoimmunology Published 25 January 2018 Crick labsDinis CaladoFull details VE-cadherin-mediated epigenetic regulation of endothelial gene expression Authors (21) Marco F Morini Costanza Giampietro Monica Corada Federica Pisati Elisa Lavarone Sara I Cunha[...] Ugo Cavallaro Diego PasiniDinis Calado Elisabetta Dejana Andrea Taddei Circulation Research Published 19 January 2018 Crick labs/ facilitiesDinis CaladoStructural BiologyPeptide ChemistryExperimental HistopathologyBioinformatics and BiostatisticsFull details Germinal center formation with retrovirally transduced B cells for determining the role of specific molecules in vivo Authors (1)Rinako Nakagawa Methods in Molecular Biology Published 7 June 2017 Crick labsDinis CaladoFull details Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration Authors (10)Michael Lattke Stephanie N Reichel Alexander Magnutzki Alireza Abaei Volker Rasche Paul WaltherDinis Calado Boris Ferger Thomas Wirth Bernd Baumann Molecular Neurodegeneration Published 13 February 2017 Crick labsFrancois GuillemotDinis CaladoFull details Thymus-derived regulatory T cell development is regulated by C-type-lectin-mediated BIC/microRNA 155 expression Authors (11) Raquel Sánchez-Díaz Rafael Blanco-Dominguez Sandra Lasarte Katerina Tsilingiri Enrique Martín-Gayo Beatriz Linillos-Pradillo Hortensia de la Fuente Francisco Sánchez-MadridRinako Nakagawa María L Toribio Pilar Martín Molecular and Cellular Biology Published 1 May 2017 Crick labsDinis CaladoFull details N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells Authors (12) Philip J Brown Duncan M Gascoyne Linden Lyne Hayley Spearman Suet Ling Felce Nora Mcfadden[...] Sharon Barrans Steven LynhamDinis Calado Malcolm Ward Alison H Banham Haematologica Published 1 July 2016 Crick labs/ facilitiesDinis CaladoBioinformatics and BiostatisticsFull details PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones Authors (12) Sandrine Sander Van Trung Chu Tomoharu Yasuda Andrew Franklin Robin GrafDinis Calado[...] Koshi Imami Matthias Selbach Michela Di Virgilio Lars Bullinger Klaus Rajewsky Immunity Published 15 December 2015 Crick labsDinis CaladoFull details The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia Authors (9) J Eswaran P Sinclair O Heidenreich J Irving LJ Russell A HallDinis Calado CJ Harrison J Vormoor Leukemia Published 6 May 2015 Crick labsDinis CaladoFull details Pagination Current page 1 Page 2 Next page Next Last page Last PublicationsYear published2021 (4)2020 (2)2019 (2)2018 (5)2017 (4)2016 (1)2015 (3) Facet Year publishedResearch topicsChemical Biology & High Throughput (21)Developmental Biology (21)Genetics & Genomics (21)Immunology (21)Model Organisms (21)Signalling & Oncogenes (21)Stem Cells (21)Tumour Biology (21)Computational & Systems Biology (6)Genome Integrity & 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Generation and surgical analysis of genetic mouse models to study NF-κB-driven pathogenesis of Diffuse Large B Cell Lymphoma Authors (5) Bernard D Maybury Yolanda Saavedra-TorresThomas Snoeks Jude FitzgibbonDinis Calado Methods in Molecular Biology Published 9 July 2021 Crick labs/ facilitiesDinis CaladoIn Vivo ImagingBiological Research FacilityFull details
Immune crosstalk between lymph nodes and breast carcinomas, with a focus on B cells Authors (4) Elena Alberts Isobelle WallDinis Calado Anita Grigoriadis Frontiers in Molecular Biosciences Published 1 May 2021 Crick labsDinis CaladoFull details
Positive selection in the light zone of germinal centers Authors (2)Rinako NakagawaDinis Calado Frontiers in Immunology Published 1 March 2021 Crick labsDinis CaladoFull details
Permissive selection followed by affinity-based proliferation of GC light zone B cells dictates cell fate and ensures clonal breadth Authors (11)Rinako Nakagawa Amparo Toboso-Navasa Marta SchipsGeorge Young Leena Bhaw-Rosun Miriam Llorian-Sopena Probir Chakravarty Abdul Karim SesayGeorge Kassiotis Michael Meyer-HermannDinis Calado Proceedings of the National Academy of Sciences of USA Published 12 January 2021 Crick labs/ facilitiesGeorge KassiotisDinis CaladoBioinformatics and BiostatisticsAdvanced SequencingLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityFull details
Genetic timestamping of plasma cells in vivo reveals tissue-specific homeostatic population turnover Authors (3) An Qi Xu Rita R BarbosaDinis Calado eLife Published 2 November 2020 Crick labs/ facilitiesDinis CaladoFlow CytometryBiological Research FacilityFull details
Restriction of memory B cell differentiation at the germinal center B cell positive selection stage Authors (13) Amparo Toboso-Navasa Arief Gunawan Giulia MorlinoRinako Nakagawa Andrea Taddei Djamil Damry[...] Martin JanzGeorge Kassiotis Robert Brink Martin EilersDinis Calado Journal of Experimental Medicine Published 6 July 2020 Crick labs/ facilitiesGeorge KassiotisDinis CaladoBioinformatics and BiostatisticsLight MicroscopyFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
RAC1P29S induces a mesenchymal phenotypic switch via serum response factor to promote melanoma development and therapy resistance Authors (17) Daniël A LionaronsDavid HancockSareena Rana Philip EastChristopher MooreMiguel Murillo[...]Ian Rosewell Ralph Fritsch Richard NeubigMiriam Molina ArcasJulian Downward Cancer Cell Published 8 July 2019 Crick labs/ facilitiesJulian DownwardDinis CaladoGenetic Modification ServiceExperimental HistopathologyBiological Research FacilityBioinformatics and BiostatisticsFull details
Validation and invalidation of chemical probes for the human N-myristoyltransferases Authors (9) Wouter W Kallemeijn Gregor A Lueg Monica Faronato Kate Hadavizadeh Andrea Goya Grocin Ok-Ryul SongMichael HowellDinis Calado Edward W Tate Cell Chemical Biology Published 20 June 2019 Crick labs/ facilitiesEd TateDinis CaladoHigh Throughput ScreeningCell ServicesFull details
MicroRNA-155 protects group 2 innate lymphoid cells from apoptosis to promote type-2 immunity Authors (8) Martin D Knolle Shau Bing Chin Batika MJ Rana Alexandros EnglezakisRinako Nakagawa Padraic G Fallon Anna Git Andrew NJ McKenzie Frontiers in Immunology Published 9 October 2018 Crick labsDinis CaladoFull details
Restoration of endogenous retrovirus infectivity impacts mouse cancer models Authors (10)Eleonora Ottina Prisca LevyUrszula Eksmond Julia MerkenschlagerGeorge Young Juliette RoelsJonathan Stoye Thomas TütingDinis CaladoGeorge Kassiotis Cancer Immunology Research Published 1 November 2018 Crick labs/ facilitiesJonathan StoyeGeorge KassiotisDinis CaladoFlow CytometryBiological Research FacilityFull details
BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma Authors (20) Kyren A Lazarus Fazal Hadi Elisabetta Zambon Karsten Bach Maria-Francesca Santolla Julie K Watson[...] Frank M McCaughan John Le Quesne Joo-Hyeon LeeDinis Calado Walid T Khaled Nature Communications Published 20 August 2018 Crick labsDinis CaladoFull details
Matrix stiffness controls lymphatic vessel formation through regulation of a GATA2-dependent transcriptional program Authors (14) Maike Frye Andrea Taddei Cathrin Dierkes Ines Martinez-Corral Matthew Fielden Henrik Ortsäter[...] Marjo Salminen Liqun He Natasha L Harvey Friedemann Kiefer Taija Mäkinen Nature Communications Published 17 April 2018 Crick labs/ facilitiesDinis CaladoFlow CytometryFull details
FOXO1 promotes resistance of non-Hodgkin lymphomas to anti-CD20-based therapy Authors (19) Beata Pyrzynska Michal Dwojak Abdessamad Zerrouqi Giulia Morlino Piotr Zapala Nina Miazek[...] Dimitar G Efremov Przemyslaw JuszczynskiDinis Calado Jakub Golab Magdalena Winiarska Oncoimmunology Published 25 January 2018 Crick labsDinis CaladoFull details
VE-cadherin-mediated epigenetic regulation of endothelial gene expression Authors (21) Marco F Morini Costanza Giampietro Monica Corada Federica Pisati Elisa Lavarone Sara I Cunha[...] Ugo Cavallaro Diego PasiniDinis Calado Elisabetta Dejana Andrea Taddei Circulation Research Published 19 January 2018 Crick labs/ facilitiesDinis CaladoStructural BiologyPeptide ChemistryExperimental HistopathologyBioinformatics and BiostatisticsFull details
Germinal center formation with retrovirally transduced B cells for determining the role of specific molecules in vivo Authors (1)Rinako Nakagawa Methods in Molecular Biology Published 7 June 2017 Crick labsDinis CaladoFull details
Transient IKK2 activation in astrocytes initiates selective non-cell-autonomous neurodegeneration Authors (10)Michael Lattke Stephanie N Reichel Alexander Magnutzki Alireza Abaei Volker Rasche Paul WaltherDinis Calado Boris Ferger Thomas Wirth Bernd Baumann Molecular Neurodegeneration Published 13 February 2017 Crick labsFrancois GuillemotDinis CaladoFull details
Thymus-derived regulatory T cell development is regulated by C-type-lectin-mediated BIC/microRNA 155 expression Authors (11) Raquel Sánchez-Díaz Rafael Blanco-Dominguez Sandra Lasarte Katerina Tsilingiri Enrique Martín-Gayo Beatriz Linillos-Pradillo Hortensia de la Fuente Francisco Sánchez-MadridRinako Nakagawa María L Toribio Pilar Martín Molecular and Cellular Biology Published 1 May 2017 Crick labsDinis CaladoFull details
N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells Authors (12) Philip J Brown Duncan M Gascoyne Linden Lyne Hayley Spearman Suet Ling Felce Nora Mcfadden[...] Sharon Barrans Steven LynhamDinis Calado Malcolm Ward Alison H Banham Haematologica Published 1 July 2016 Crick labs/ facilitiesDinis CaladoBioinformatics and BiostatisticsFull details
PI3 kinase and FOXO1 transcription factor activity differentially control B cells in the germinal center light and dark zones Authors (12) Sandrine Sander Van Trung Chu Tomoharu Yasuda Andrew Franklin Robin GrafDinis Calado[...] Koshi Imami Matthias Selbach Michela Di Virgilio Lars Bullinger Klaus Rajewsky Immunity Published 15 December 2015 Crick labsDinis CaladoFull details
The pre-B-cell receptor checkpoint in acute lymphoblastic leukaemia Authors (9) J Eswaran P Sinclair O Heidenreich J Irving LJ Russell A HallDinis Calado CJ Harrison J Vormoor Leukemia Published 6 May 2015 Crick labsDinis CaladoFull details
