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Breadcrumb Michele Mishto Mishto lab Molecular Immunology lab : Publications Lab contentLab contentIn this section Overview Members Publications Publications Displaying 1 - 20 of 23Last updated : 31 January 2023 03:43 Mechanistic diversity in MHC class I antigen recognition Authors (4)Camila Barbosa Justin Barton Adrian J Shepherd Michele Mishto Biochemical Journal Published 15 December 2021 Crick labsMichele MishtoFull details Commentary: Are there indeed spliced peptides in the immunopeptidome? Authors (1) Michele Mishto Molecular and Cellular Proteomics Published 2 October 2021 Crick labsMichele MishtoFull details Response: Commentary: An In Silico-In Vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients Authors (5) Michele Mishto Guillermo Rodriguez-Hernandez Jacques Neefjes Henning Urlaub Juliane Liepe Frontiers in Immunology Published 13 July 2021 Crick labsMichele MishtoFull details Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides Authors (12) Alessia Melacarne Valentina Ferrari Luca Tiraboschi Michele Mishto Juliane Liepe Marina Aralla[...] Michela Lizier Chiara Pozzi Offer Zeira Giuseppe Penna Maria Rescigno Cell Reports Published 6 July 2021 Crick labsMichele MishtoFull details Potential mimicry of viral and pancreatic β cell antigens through non-spliced and cis-spliced zwitter epitope candidates in type 1 diabetes Authors (4) Michele Mishto Artem Mansurkhodzhaev Teresa Rodriguez-Calvo Juliane Liepe Frontiers in Immunology Published 15 April 2021 Crick labsMichele MishtoFull details Proteasome-generated cis-spliced peptides and their potential role in CD8+ T cell tolerance Authors (4) Artem Mansurkhodzhaev Camila RR Barbosa Michele Mishto Juliane Liepe Frontiers in Immunology Published 24 February 2021 Crick labsMichele MishtoFull details What we see, what we do not see, and what we do not want to see in HLA class I immunopeptidomes Authors (1) Michele Mishto Proteomics Published 1 August 2020 Crick labsMichele MishtoFull details Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes Authors (8) Gerd Specht Hanna P Roetschke Artem Mansurkhodzhaev Petra Henklein Kathrin Textoris-Taube Henning Urlaub Michele Mishto Juliane Liepe Scientific Data Published 15 May 2020 Crick labsMichele MishtoFull details An in silico-in vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients Authors (13) Michele Mishto Artem Mansurkhodzhaev Ge Ying Aruna Bitra Robert A Cordfunke Sarah Henze[...] Henning Urlaub Jacques Neefjes Alessandro Sette Dirk M Zajonc Juliane Liepe Frontiers in Immunology Published 15 November 2019 Crick labsMichele MishtoFull details ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope Authors (14) Kathrin Textoris-Taube Clemens Cammann Petra Henklein Eylin Topfstedt Frédéric Ebstein Sarah Henze[...] Burkhardt Dahlmann Wolfgang Uckert Annette Paschen Michele Mishto Ulrike Seifert European Journal of Immunology Published 1 February 2020 Crick labsMichele MishtoFull details Proteolytic dynamics of human 20S thymoproteasome Authors (10) Ulrike Kuckelkorn Sabine Stübler Kathrin Textoris-Taube Christiane Kilian Agathe Niewienda Petra Henklein Katharina Janek Michael PH Stumpf Michele Mishto Juliane Liepe Journal of Biological Chemistry Published 10 May 2019 Crick labsMichele MishtoFull details Mapping the MHC class I-spliced immunopeptidome of cancer cells Authors (5) Juliane Liepe John Sidney Felix KM Lorenz Alessandro Sette Michele Mishto Cancer Immunology Research Published 1 January 2019 Crick labsMichele MishtoFull details NMDA-receptor inhibition and oxidative stress during hippocampal maturation differentially alter parvalbumin expression and gamma-band activity Authors (7) Luisa A Hasam-Henderson Grace C Gotti Michele Mishto Constantin Klisch Zoltan Gerevich Jörg RP Geiger Richard Kovács Scientific Reports Published 22 June 2018 Crick labsMichele MishtoFull details Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? Authors (3) Juliane Liepe Huib Ovaa Michele Mishto Current Opinion in Immunology Published 1 June 2018 Crick labsMichele MishtoFull details An unexpected major role for proteasome-catalyzed peptide splicing in generation of T cell epitopes: Is there relevance for vaccine development? Authors (5) ACM Platteel J Liepe W van Eden M Mishto AJAM Sijts Frontiers in Immunology Published 3 November 2017 Crick labsMichele MishtoFull details Post-translational peptide splicing and T cell responses Authors (2) Michele Mishto Juliane Liepe Trends in Immunology Published 1 December 2017 Crick labsMichele MishtoFull details Multi-level strategy for identifying proteasome-catalyzed spliced epitopes targeted by CD8+ T cells during bacterial infection Authors (10) Anouk CM Platteel Juliane Liepe Kathrin Textoris-Taube Christin Keller Petra Henklein Hanna H Schalkwijk Rebeca Cardoso Peter M Kloetzel Michele Mishto Alice JAM Sijts Cell Reports Published 1 August 2017 Crick labsMichele MishtoFull details Neuroinflammatory targets and treatments for epilepsy validated in experimental models Authors (18) Eleonora Aronica Sebastian Bauer Yuri Bozzi Matteo Caleo Raymond Dingledine Jan A Gorter[...] Eleonora Palma Michael O Poulter Gaetano Terrone Annamaria Vezzani Rafal M Kaminski Epilepsia Published 1 July 2017 Crick labsMichele MishtoFull details Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis Authors (26) Chiara Dianzani Elena Bellavista Juliane Liepe Claudia Verderio Morena Martucci Aurelia Santoro[...] Daniela Galimberti Filippo Martinelli Boneschi Cristoforo Comi Umberto Dianzani Michele Mishto Scientific Reports Published 9 March 2017 Crick labsMichele MishtoFull details A large fraction of HLA class I ligands are proteasome-generated spliced peptides Authors (10) Juliane Liepe Fabio Marino John Sidney Anita Jeko Daniel E Bunting Alessandro Sette Peter M Kloetzel Michael PH Stumpf Albert JR Heck Michele Mishto Science Published 21 October 2016 Crick labsMichele MishtoFull details Pagination Current page 1 Page 2 Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Mechanistic diversity in MHC class I antigen recognition Authors (4)Camila Barbosa Justin Barton Adrian J Shepherd Michele Mishto Biochemical Journal Published 15 December 2021 Crick labsMichele MishtoFull details
Commentary: Are there indeed spliced peptides in the immunopeptidome? Authors (1) Michele Mishto Molecular and Cellular Proteomics Published 2 October 2021 Crick labsMichele MishtoFull details
Response: Commentary: An In Silico-In Vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients Authors (5) Michele Mishto Guillermo Rodriguez-Hernandez Jacques Neefjes Henning Urlaub Juliane Liepe Frontiers in Immunology Published 13 July 2021 Crick labsMichele MishtoFull details
Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides Authors (12) Alessia Melacarne Valentina Ferrari Luca Tiraboschi Michele Mishto Juliane Liepe Marina Aralla[...] Michela Lizier Chiara Pozzi Offer Zeira Giuseppe Penna Maria Rescigno Cell Reports Published 6 July 2021 Crick labsMichele MishtoFull details
Potential mimicry of viral and pancreatic β cell antigens through non-spliced and cis-spliced zwitter epitope candidates in type 1 diabetes Authors (4) Michele Mishto Artem Mansurkhodzhaev Teresa Rodriguez-Calvo Juliane Liepe Frontiers in Immunology Published 15 April 2021 Crick labsMichele MishtoFull details
Proteasome-generated cis-spliced peptides and their potential role in CD8+ T cell tolerance Authors (4) Artem Mansurkhodzhaev Camila RR Barbosa Michele Mishto Juliane Liepe Frontiers in Immunology Published 24 February 2021 Crick labsMichele MishtoFull details
What we see, what we do not see, and what we do not want to see in HLA class I immunopeptidomes Authors (1) Michele Mishto Proteomics Published 1 August 2020 Crick labsMichele MishtoFull details
Large database for the analysis and prediction of spliced and non-spliced peptide generation by proteasomes Authors (8) Gerd Specht Hanna P Roetschke Artem Mansurkhodzhaev Petra Henklein Kathrin Textoris-Taube Henning Urlaub Michele Mishto Juliane Liepe Scientific Data Published 15 May 2020 Crick labsMichele MishtoFull details
An in silico-in vitro pipeline identifying an HLA-A*02:01+ KRAS G12V+ spliced epitope candidate for a broad tumor-immune response in cancer patients Authors (13) Michele Mishto Artem Mansurkhodzhaev Ge Ying Aruna Bitra Robert A Cordfunke Sarah Henze[...] Henning Urlaub Jacques Neefjes Alessandro Sette Dirk M Zajonc Juliane Liepe Frontiers in Immunology Published 15 November 2019 Crick labsMichele MishtoFull details
ER-aminopeptidase 1 determines the processing and presentation of an immunotherapy-relevant melanoma epitope Authors (14) Kathrin Textoris-Taube Clemens Cammann Petra Henklein Eylin Topfstedt Frédéric Ebstein Sarah Henze[...] Burkhardt Dahlmann Wolfgang Uckert Annette Paschen Michele Mishto Ulrike Seifert European Journal of Immunology Published 1 February 2020 Crick labsMichele MishtoFull details
Proteolytic dynamics of human 20S thymoproteasome Authors (10) Ulrike Kuckelkorn Sabine Stübler Kathrin Textoris-Taube Christiane Kilian Agathe Niewienda Petra Henklein Katharina Janek Michael PH Stumpf Michele Mishto Juliane Liepe Journal of Biological Chemistry Published 10 May 2019 Crick labsMichele MishtoFull details
Mapping the MHC class I-spliced immunopeptidome of cancer cells Authors (5) Juliane Liepe John Sidney Felix KM Lorenz Alessandro Sette Michele Mishto Cancer Immunology Research Published 1 January 2019 Crick labsMichele MishtoFull details
NMDA-receptor inhibition and oxidative stress during hippocampal maturation differentially alter parvalbumin expression and gamma-band activity Authors (7) Luisa A Hasam-Henderson Grace C Gotti Michele Mishto Constantin Klisch Zoltan Gerevich Jörg RP Geiger Richard Kovács Scientific Reports Published 22 June 2018 Crick labsMichele MishtoFull details
Why do proteases mess up with antigen presentation by re-shuffling antigen sequences? Authors (3) Juliane Liepe Huib Ovaa Michele Mishto Current Opinion in Immunology Published 1 June 2018 Crick labsMichele MishtoFull details
An unexpected major role for proteasome-catalyzed peptide splicing in generation of T cell epitopes: Is there relevance for vaccine development? Authors (5) ACM Platteel J Liepe W van Eden M Mishto AJAM Sijts Frontiers in Immunology Published 3 November 2017 Crick labsMichele MishtoFull details
Post-translational peptide splicing and T cell responses Authors (2) Michele Mishto Juliane Liepe Trends in Immunology Published 1 December 2017 Crick labsMichele MishtoFull details
Multi-level strategy for identifying proteasome-catalyzed spliced epitopes targeted by CD8+ T cells during bacterial infection Authors (10) Anouk CM Platteel Juliane Liepe Kathrin Textoris-Taube Christin Keller Petra Henklein Hanna H Schalkwijk Rebeca Cardoso Peter M Kloetzel Michele Mishto Alice JAM Sijts Cell Reports Published 1 August 2017 Crick labsMichele MishtoFull details
Neuroinflammatory targets and treatments for epilepsy validated in experimental models Authors (18) Eleonora Aronica Sebastian Bauer Yuri Bozzi Matteo Caleo Raymond Dingledine Jan A Gorter[...] Eleonora Palma Michael O Poulter Gaetano Terrone Annamaria Vezzani Rafal M Kaminski Epilepsia Published 1 July 2017 Crick labsMichele MishtoFull details
Extracellular proteasome-osteopontin circuit regulates cell migration with implications in multiple sclerosis Authors (26) Chiara Dianzani Elena Bellavista Juliane Liepe Claudia Verderio Morena Martucci Aurelia Santoro[...] Daniela Galimberti Filippo Martinelli Boneschi Cristoforo Comi Umberto Dianzani Michele Mishto Scientific Reports Published 9 March 2017 Crick labsMichele MishtoFull details
A large fraction of HLA class I ligands are proteasome-generated spliced peptides Authors (10) Juliane Liepe Fabio Marino John Sidney Anita Jeko Daniel E Bunting Alessandro Sette Peter M Kloetzel Michael PH Stumpf Albert JR Heck Michele Mishto Science Published 21 October 2016 Crick labsMichele MishtoFull details
