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Breadcrumb Paul Nurse Nurse lab Cell Cycle Laboratory : Publications Lab contentLab contentIn this section Overview Areas of interest Publications Members Vacancies Schizosaccharomyces pombe cells expressing cdc2-mNeonGreen (green), and cell walls stained with Calcofluor (magenta). Toggle to view hero caption PublicationsYear published2021 (4)2020 (1)2018 (1)2017 (2) Facet Year publishedResearch topicsBiochemistry & Proteomics (8)Cell Biology (8)Cell Cycle & Chromosomes (8)Chemical Biology & High Throughput (8)Computational & Systems Biology (8)Genetics & Genomics (8)Model Organisms (8)Synthetic Biology (8)Structural Biology & Biophysics (6)Infectious Disease (5)Immunology (4)Tumour Biology (4)Human Biology & Physiology (2)Imaging (2)Signalling & Oncogenes (2)Developmental Biology (1)Gene Expression (1)Metabolism (1)Microfabrication & Bioengineering (1)Neurosciences (1)Stem Cells (1) (-)Genome Integrity & Repair (8) Facet Research topicsPublication typeJournal article (8)Primary research (8) Facet Publication typeJournalBiochemical Journal (3)Cancer Discovery (1)Journal of Cell Science (1)Nucleic Acids Research (1)RSC Advances: an international journal to further the chemical sciences (1)The Lancet (1) Facet Journal Publications Displaying 1 - 8 of 8Last updated : 13 August 2022 02:20 Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease Authors (22)Jennifer MilliganTheresa ZeisnerGeorge PapageorgiouDhira JoshiChristelle SoudyRachel Ulferts[...]Michael HowellRupert Beale Karim LabibNicola O'ReillyJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyRupert BealePeptide ChemistryHigh Throughput ScreeningFull details Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase Authors (21)Saz BasuTiffany MakRachel UlfertsMary Wu Tom Deegan Ryo Fujisawa[...]Rupert Beale Victoria H CowlingMichael Howell Karim LabibJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyRupert BealeHigh Throughput ScreeningFull details Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease Authors (19)Berta CanalAllison McClureJoseph CurranMary WuRachel UlfertsFlorian Weissmann[...]Clovis Basier Karim LabibRupert BealeMichael HowellJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyRupert BealeHigh Throughput ScreeningStructural BiologyFermentationFull details An improved method for the incorporation of fluoromethyl ketones into solid phase peptide synthesis techniques Authors (6)Dhira JoshiJennifer MilliganTheresa ZeisnerNicola O'ReillyJohn DiffleyGeorge Papageorgiou RSC Advances: an international journal to further the chemical sciences Published 8 June 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyPeptide ChemistryMRC Biomedical NMR CentreFull details Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyPeptide ChemistryMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenomics/Equipment ParkGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details Fission yeast telosomes: non-canonical histone-containing chromatin structures dependent on shelterin and RNA Authors (4)Jessica Greenwood Harshil Patel Thomas R Cech Julia Promisel Cooper Nucleic Acids Research Published 28 September 2018 Crick labs/ facilitiesPaul NurseBioinformatics and BiostatisticsFull details Phosphorylation of the RNA binding protein Zfs1 modulates sexual differentiation in fission yeast Authors (3) Francisco J Navarro Probir ChakravartyPaul Nurse Journal of Cell Science Published 15 December 2017 Crick labs/ facilitiesPaul NurseBioinformatics and BiostatisticsAdvanced SequencingFull details APC/C dysfunction limits excessive cancer chromosomal instability Authors (18) Laurent Sansregret James O Patterson Sally Dewhurst Carlos López-García André Koch Nicholas McGranahan[...] Martin R Singleton René H MedemaPaul Nurse Mark PetronczkiCharles Swanton Cancer Discovery Published 1 February 2017 Crick labs/ facilitiesMichael WayCharles SwantonMartin SingletonPaul NurseLight MicroscopyHigh Throughput ScreeningBioinformatics and BiostatisticsFull details Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease Authors (22)Jennifer MilliganTheresa ZeisnerGeorge PapageorgiouDhira JoshiChristelle SoudyRachel Ulferts[...]Michael HowellRupert Beale Karim LabibNicola O'ReillyJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyRupert BealePeptide ChemistryHigh Throughput ScreeningFull details
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase Authors (21)Saz BasuTiffany MakRachel UlfertsMary Wu Tom Deegan Ryo Fujisawa[...]Rupert Beale Victoria H CowlingMichael Howell Karim LabibJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyRupert BealeHigh Throughput ScreeningFull details
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease Authors (19)Berta CanalAllison McClureJoseph CurranMary WuRachel UlfertsFlorian Weissmann[...]Clovis Basier Karim LabibRupert BealeMichael HowellJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyRupert BealeHigh Throughput ScreeningStructural BiologyFermentationFull details
An improved method for the incorporation of fluoromethyl ketones into solid phase peptide synthesis techniques Authors (6)Dhira JoshiJennifer MilliganTheresa ZeisnerNicola O'ReillyJohn DiffleyGeorge Papageorgiou RSC Advances: an international journal to further the chemical sciences Published 8 June 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyPeptide ChemistryMRC Biomedical NMR CentreFull details
Pandemic peak SARS-CoV-2 infection and seroconversion rates in London frontline health-care workers Authors (341) Catherine F Houlihan Nina Vora Thomas Byrne Dan LewerGavin Kelly Judith Heaney[...] Andrew Hayward Richard Gilson Gavin KellyFiona Roberts Emine Hatipoglu The Lancet Published 25 July 2020 Crick labs/ facilitiesAndreas WackKaren VousdenJernej UleJames TurnerMoritz TreeckCharles SwantonAdam SaterialeErik SahaiCaetano Reis e SousaPeter RatcliffeLucia Prieto-GodinoVenizelos PapayannopoulosAnne O’GarraPaul NurseGeorge KassiotisMaximiliano GutierrezSonia GandhiSteve GamblinPeter Cherepanov Luiz Pedro CarvalhoDominique BonnetMike BlackmanRupert BealeWorldwide Influenza CentreStructural BiologyPeptide ChemistryMetabolomicsHuman Embryonic Stem CellHigh Throughput ScreeningGenomics/Equipment ParkGenetic Modification ServiceFlow CytometryFermentationExperimental HistopathologyElectron MicroscopyCell ServicesBiological Research FacilityBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
Fission yeast telosomes: non-canonical histone-containing chromatin structures dependent on shelterin and RNA Authors (4)Jessica Greenwood Harshil Patel Thomas R Cech Julia Promisel Cooper Nucleic Acids Research Published 28 September 2018 Crick labs/ facilitiesPaul NurseBioinformatics and BiostatisticsFull details
Phosphorylation of the RNA binding protein Zfs1 modulates sexual differentiation in fission yeast Authors (3) Francisco J Navarro Probir ChakravartyPaul Nurse Journal of Cell Science Published 15 December 2017 Crick labs/ facilitiesPaul NurseBioinformatics and BiostatisticsAdvanced SequencingFull details
APC/C dysfunction limits excessive cancer chromosomal instability Authors (18) Laurent Sansregret James O Patterson Sally Dewhurst Carlos López-García André Koch Nicholas McGranahan[...] Martin R Singleton René H MedemaPaul Nurse Mark PetronczkiCharles Swanton Cancer Discovery Published 1 February 2017 Crick labs/ facilitiesMichael WayCharles SwantonMartin SingletonPaul NurseLight MicroscopyHigh Throughput ScreeningBioinformatics and BiostatisticsFull details
