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Breadcrumb Experimental Histopathology Experimental Histopathology : Publications Lab contentLab contentIn this section Overview Publications Members Publications Displaying 1 - 10 of 186Last updated : 30 March 2023 02:30 Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion Authors (27) Elizabeth R Murray Shinelle Menezes Jack C Henry Josie L Williams Lorena Alba-Castellón Priththivika Baskaran[...] Nuria Gavara Oliver Pearce Pedro Cutillas John F Marshall Angus JM Cameron Cell Reports Published 25 January 2022 Crick labs/ facilitiesPeter ParkerGenetic Modification ServiceBiological Research FacilityExperimental HistopathologyFull details Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study Authors (35)Xiao Fu Yue Zhao Jose I LopezAndrew RowanLewis AuAnnika Fendler[...]Erik SahaiKevin LitchfieldSamra Turajlic TRACERx Renal ConsortiumPaul Bates Nature Ecology and Evolution Published 1 January 2022 Crick labs/ facilitiesSamra TurajlicCharles SwantonErik SahaiPaul BatesExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingFull details CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes Authors (8)Charlotte DouglasValdone MaciulyteJasmin ZohrenDaniel SnellShantha MahadevaiahAndrew Ojarikre Peter JI EllisJames Turner Nature Communications Published 3 December 2021 Crick labs/ facilitiesJames TurnerLight MicroscopyIn Vivo ImagingGenetic Modification ServiceFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details Regulation of intestinal immunity and tissue repair by enteric glia Authors (18)Franze ProgatzkyMichael ShapiroSong Hui Chng Bethania Garcia-CassaniCajsa Classon Selin Sevgi[...] Lewis J Entwistle Alejandro Suárez-Bonnet Mark WilsonBrigitta StockingerVassilis Pachnis Nature Published 20 October 2021 Crick labs/ facilitiesGitta StockingerVassilis PachnisExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma Authors (207)Lewis Au Emine Hatipoglu Marc Robert de MassyKevin Litchfield Gordon BeattieAndrew Rowan[...] Jonathon Olsburgh Alexander Polson Sarah Rudman Mary Varia Hema Verma Cancer Cell Published 8 November 2021 Crick labs/ facilitiesSamra TurajlicCharles SwantonGeorge KassiotisBioinformatics and BiostatisticsAdvanced SequencingExperimental HistopathologyFull details Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study Authors (89)Annika FendlerLewis AuScott ShepherdFiona ByrneMaddalena Cerrone Laura Amanda Boos[...]George Kassiotis James LarkinRobert WilkinsonSamra Turajlic The CAPTURE consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinWorldwide Influenza CentreProteomicsMetabolomicsHigh Throughput ScreeningFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details USP28 deletion and small molecule inhibition destabilises c-MYC and elicits regression of squamous cell lung carcinoma Authors (32)Josue Ruiz Adan Pinto-Fernandez Andrew P TurnbullLinxiang Lan Thomas M Charlton Hannah Claire Scott[...] David Komander Sylvie Urbé Michael J Clague Benedikt M KesslerAxel Behrens eLife Published 12 October 2021 Crick labs/ facilitiesAxel BehrensGenetic Modification ServiceExperimental HistopathologyBiological Research FacilityFull details Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry Authors (18)Febe Van MaldegemKarishma ValandMegan Cole Harshil PatelMihaela AngelovaSareena Rana[...]Philip HobsonDina LeviMiriam Molina ArcasCharles SwantonJulian Downward Nature Communications Published 8 October 2021 Crick labs/ facilitiesCharles SwantonJulian DownwardFlow CytometryBioinformatics and BiostatisticsScientific computingLight MicroscopyExperimental HistopathologyCell ServicesBiological Research FacilityFull details A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza Authors (6)Julie RappeKatja FinsterbuschStefania Crotta Matthias Mack Simon L PriestnallAndreas Wack Journal of Experimental Medicine Published 1 November 2021 Crick labs/ facilitiesAndreas WackExperimental HistopathologyFlow CytometryBiological Research FacilityFull details Single cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human specific features Authors (4)Teresa Rayon AlonsoRory Maizels Christopher BarringtonJames Briscoe Development Published 16 July 2021 Crick labs/ facilitiesJames BriscoeBioinformatics and BiostatisticsScientific computingExperimental HistopathologyAdvanced SequencingFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion Authors (27) Elizabeth R Murray Shinelle Menezes Jack C Henry Josie L Williams Lorena Alba-Castellón Priththivika Baskaran[...] Nuria Gavara Oliver Pearce Pedro Cutillas John F Marshall Angus JM Cameron Cell Reports Published 25 January 2022 Crick labs/ facilitiesPeter ParkerGenetic Modification ServiceBiological Research FacilityExperimental HistopathologyFull details
Spatial patterns of tumour growth impact clonal diversification in a computational model and the TRACERx Renal study Authors (35)Xiao Fu Yue Zhao Jose I LopezAndrew RowanLewis AuAnnika Fendler[...]Erik SahaiKevin LitchfieldSamra Turajlic TRACERx Renal ConsortiumPaul Bates Nature Ecology and Evolution Published 1 January 2022 Crick labs/ facilitiesSamra TurajlicCharles SwantonErik SahaiPaul BatesExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingFull details
CRISPR-Cas9 effectors facilitate generation of single-sex litters and sex-specific phenotypes Authors (8)Charlotte DouglasValdone MaciulyteJasmin ZohrenDaniel SnellShantha MahadevaiahAndrew Ojarikre Peter JI EllisJames Turner Nature Communications Published 3 December 2021 Crick labs/ facilitiesJames TurnerLight MicroscopyIn Vivo ImagingGenetic Modification ServiceFlow CytometryExperimental HistopathologyBiological Research FacilityAdvanced SequencingFull details
Regulation of intestinal immunity and tissue repair by enteric glia Authors (18)Franze ProgatzkyMichael ShapiroSong Hui Chng Bethania Garcia-CassaniCajsa Classon Selin Sevgi[...] Lewis J Entwistle Alejandro Suárez-Bonnet Mark WilsonBrigitta StockingerVassilis Pachnis Nature Published 20 October 2021 Crick labs/ facilitiesGitta StockingerVassilis PachnisExperimental HistopathologyBioinformatics and BiostatisticsFlow CytometryBiological Research FacilityAdvanced SequencingFull details
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma Authors (207)Lewis Au Emine Hatipoglu Marc Robert de MassyKevin Litchfield Gordon BeattieAndrew Rowan[...] Jonathon Olsburgh Alexander Polson Sarah Rudman Mary Varia Hema Verma Cancer Cell Published 8 November 2021 Crick labs/ facilitiesSamra TurajlicCharles SwantonGeorge KassiotisBioinformatics and BiostatisticsAdvanced SequencingExperimental HistopathologyFull details
Functional antibody and T cell immunity following SARS-CoV-2 infection, including by variants of concern, in patients with cancer: the CAPTURE study Authors (89)Annika FendlerLewis AuScott ShepherdFiona ByrneMaddalena Cerrone Laura Amanda Boos[...]George Kassiotis James LarkinRobert WilkinsonSamra Turajlic The CAPTURE consortium Nature Cancer Published 1 December 2021 Crick labs/ facilitiesRobert J WilkinsonSamra TurajlicCharles SwantonJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinWorldwide Influenza CentreProteomicsMetabolomicsHigh Throughput ScreeningFlow CytometryExperimental HistopathologyBioinformatics and BiostatisticsAdvanced SequencingScientific computingFull details
USP28 deletion and small molecule inhibition destabilises c-MYC and elicits regression of squamous cell lung carcinoma Authors (32)Josue Ruiz Adan Pinto-Fernandez Andrew P TurnbullLinxiang Lan Thomas M Charlton Hannah Claire Scott[...] David Komander Sylvie Urbé Michael J Clague Benedikt M KesslerAxel Behrens eLife Published 12 October 2021 Crick labs/ facilitiesAxel BehrensGenetic Modification ServiceExperimental HistopathologyBiological Research FacilityFull details
Characterisation of tumour microenvironment remodelling following oncogene inhibition in preclinical studies with imaging mass cytometry Authors (18)Febe Van MaldegemKarishma ValandMegan Cole Harshil PatelMihaela AngelovaSareena Rana[...]Philip HobsonDina LeviMiriam Molina ArcasCharles SwantonJulian Downward Nature Communications Published 8 October 2021 Crick labs/ facilitiesCharles SwantonJulian DownwardFlow CytometryBioinformatics and BiostatisticsScientific computingLight MicroscopyExperimental HistopathologyCell ServicesBiological Research FacilityFull details
A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza Authors (6)Julie RappeKatja FinsterbuschStefania Crotta Matthias Mack Simon L PriestnallAndreas Wack Journal of Experimental Medicine Published 1 November 2021 Crick labs/ facilitiesAndreas WackExperimental HistopathologyFlow CytometryBiological Research FacilityFull details
Single cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human specific features Authors (4)Teresa Rayon AlonsoRory Maizels Christopher BarringtonJames Briscoe Development Published 16 July 2021 Crick labs/ facilitiesJames BriscoeBioinformatics and BiostatisticsScientific computingExperimental HistopathologyAdvanced SequencingFull details
