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Breadcrumb Peptide Chemistry Peptide Chemistry : Publications Lab contentLab contentIn this section Overview Areas of Interest Publications Members Potassium permanganate stain on thin layer chromatography reveals the success of chemical synthesis. Toggle to view hero caption Publications Displaying 1 - 10 of 97Last updated : 01 February 2023 02:34 Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability Authors (19) Charlotte Hodson Jason KK Low Sylvie van Twest Samuel E Jones Paolo Swuec Vincent Murphy[...] Michael W Parker Joel P Mackay Andrew N BlackfordAlessandro Costa Andrew J Deans Proceedings of the National Academy of Sciences of USA Published 8 February 2022 Crick labs/ facilitiesAlessandro CostaPeptide ChemistryFull details A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division Authors (12)Silvia MartiniKhalil DavisRupert Faraway Lisa ElzeNicola LockwoodAndrew Jones[...]Neil McDonald David J Mann Alan ArmstrongJernej UlePeter Parker Nature Communications Published 26 November 2021 Crick labs/ facilitiesJernej UlePeter ParkerPaul NurseNeil McDonaldProteomicsPeptide ChemistryLight MicroscopyFull details Involvement of oxidative and endoplasmic reticulum stress in RDH12-related retinopathies Authors (3)Hajrah Sarkar Maria TomsMariya Moosajee International Journal of Molecular Sciences Published 18 August 2021 Crick labs/ facilitiesMariya MoosajeePeptide ChemistryElectron MicroscopyFull details Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients Authors (86) Edward J Carr Mary Wu Ruth Harvey Emma C WallGavin KellySaira Hussain[...]Emma RussellAndy RiddellSvend KjaerAnnabel BorgChloe Roustan The Lancet Published 18 September 2021 Crick labs/ facilitiesCharles SwantonGitta StockingerJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyPeptide ChemistryHigh Throughput ScreeningFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsScientific computingAdvanced SequencingFull details Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation Authors (2)Allison McClureJohn Diffley eLife Published 13 August 2021 Crick labs/ facilitiesJohn DiffleyStructural BiologyProteomicsPeptide ChemistryFermentationFull details Fluorescent amino acid initiated de novo cyclic peptides for the label-free assessment of cell permeability Authors (6)Yuteng Wu M Teresa Bertran James RowleyEwen CalderDhira JoshiLouise Walport ChemMedChem Published 15 October 2021 Crick labs/ facilitiesLouise WalportPeptide ChemistryLight MicroscopyFlow CytometryFull details Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease Authors (22)Jennifer MilliganTheresa ZeisnerGeorge PapageorgiouDhira JoshiChristelle SoudyRachel Ulferts[...]Michael HowellRupert Beale Karim LabibNicola O'ReillyJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyRupert BealePeptide ChemistryHigh Throughput ScreeningFull details Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease Authors (19)Chew Theng LimKang Wei TanMary WuRachel Ulferts Lee A ArmstrongEiko Ozono[...]Nicola O'ReillyRupert Beale Yogesh Kulathu Karim LabibJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesJohn DiffleyRupert BealePeptide ChemistryHigh Throughput ScreeningFull details Co-ordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention Authors (14)Lisa WatsonTanya SolimanKhalil Davis Joanna KellyNicola Lockwood Xiaoping Yang[...]Neil McDonald David J Mann Alan Armstrong Ulrike EggertPeter Parker Biochemical Journal Published 25 June 2021 Crick labs/ facilitiesPeter ParkerNeil McDonaldStructural BiologyPeptide ChemistryFull details Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy Authors (13)Thomas Mercer Yohei Ohashi Stefan BoeingHarold JefferiesStefano De Tito Helen Flynn[...]Martina WirthDavid FrithBram Snijders Roger Lee WilliamsSharon Tooze The EMBO Journal Published 15 July 2021 Crick labs/ facilitiesSharon ToozeProteomicsBioinformatics and BiostatisticsPeptide ChemistryHigh Throughput ScreeningGenomics/Equipment ParkFull details Pagination Current page 1 Page 2 Page 3 Page 4 Page 5 Page 6 Page 7 Page 8 Page 9 … Next page Next Last page Last Share the page Share on Twitter Share on Facebook Share on LinkedIn Share on Email
Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability Authors (19) Charlotte Hodson Jason KK Low Sylvie van Twest Samuel E Jones Paolo Swuec Vincent Murphy[...] Michael W Parker Joel P Mackay Andrew N BlackfordAlessandro Costa Andrew J Deans Proceedings of the National Academy of Sciences of USA Published 8 February 2022 Crick labs/ facilitiesAlessandro CostaPeptide ChemistryFull details
A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division Authors (12)Silvia MartiniKhalil DavisRupert Faraway Lisa ElzeNicola LockwoodAndrew Jones[...]Neil McDonald David J Mann Alan ArmstrongJernej UlePeter Parker Nature Communications Published 26 November 2021 Crick labs/ facilitiesJernej UlePeter ParkerPaul NurseNeil McDonaldProteomicsPeptide ChemistryLight MicroscopyFull details
Involvement of oxidative and endoplasmic reticulum stress in RDH12-related retinopathies Authors (3)Hajrah Sarkar Maria TomsMariya Moosajee International Journal of Molecular Sciences Published 18 August 2021 Crick labs/ facilitiesMariya MoosajeePeptide ChemistryElectron MicroscopyFull details
Neutralising antibodies after COVID-19 vaccination in UK haemodialysis patients Authors (86) Edward J Carr Mary Wu Ruth Harvey Emma C WallGavin KellySaira Hussain[...]Emma RussellAndy RiddellSvend KjaerAnnabel BorgChloe Roustan The Lancet Published 18 September 2021 Crick labs/ facilitiesCharles SwantonGitta StockingerJohn McCauleyGeorge KassiotisSonia GandhiSteve GamblinRupert BealeDavid LV BauerWorldwide Influenza CentreStructural BiologyPeptide ChemistryHigh Throughput ScreeningFlow CytometryBiological Research FacilityBioinformatics and BiostatisticsScientific computingAdvanced SequencingFull details
Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation Authors (2)Allison McClureJohn Diffley eLife Published 13 August 2021 Crick labs/ facilitiesJohn DiffleyStructural BiologyProteomicsPeptide ChemistryFermentationFull details
Fluorescent amino acid initiated de novo cyclic peptides for the label-free assessment of cell permeability Authors (6)Yuteng Wu M Teresa Bertran James RowleyEwen CalderDhira JoshiLouise Walport ChemMedChem Published 15 October 2021 Crick labs/ facilitiesLouise WalportPeptide ChemistryLight MicroscopyFlow CytometryFull details
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp5 main protease Authors (22)Jennifer MilliganTheresa ZeisnerGeorge PapageorgiouDhira JoshiChristelle SoudyRachel Ulferts[...]Michael HowellRupert Beale Karim LabibNicola O'ReillyJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesPaul NurseJohn DiffleyRupert BealePeptide ChemistryHigh Throughput ScreeningFull details
Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp3 papain-like protease Authors (19)Chew Theng LimKang Wei TanMary WuRachel Ulferts Lee A ArmstrongEiko Ozono[...]Nicola O'ReillyRupert Beale Yogesh Kulathu Karim LabibJohn Diffley Biochemical Journal Published 16 July 2021 Crick labs/ facilitiesJohn DiffleyRupert BealePeptide ChemistryHigh Throughput ScreeningFull details
Co-ordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention Authors (14)Lisa WatsonTanya SolimanKhalil Davis Joanna KellyNicola Lockwood Xiaoping Yang[...]Neil McDonald David J Mann Alan Armstrong Ulrike EggertPeter Parker Biochemical Journal Published 25 June 2021 Crick labs/ facilitiesPeter ParkerNeil McDonaldStructural BiologyPeptide ChemistryFull details
Phosphoproteomic identification of ULK substrates reveals VPS15-dependent ULK/VPS34 interplay in the regulation of autophagy Authors (13)Thomas Mercer Yohei Ohashi Stefan BoeingHarold JefferiesStefano De Tito Helen Flynn[...]Martina WirthDavid FrithBram Snijders Roger Lee WilliamsSharon Tooze The EMBO Journal Published 15 July 2021 Crick labs/ facilitiesSharon ToozeProteomicsBioinformatics and BiostatisticsPeptide ChemistryHigh Throughput ScreeningGenomics/Equipment ParkFull details
