B cells producing type I IFN modulate macrophage polarization in tuberculosis

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Authors list

Alan Bénard Imme Sakwa Pablo Schierloh André Colom Ingrid Mercier Ludovic Tailleux Luc Jouneau Pierre Boudinot Talal Al-Saati Roland Lang Jan Rehwinkel Andre G Loxton Stefan HE Kaufmann Véronique Anton-Leberre Anne O'Garra Maria Del Carmen Sasiain Brigitte Gicquel Simon Fillatreau Olivier Neyrolles Denis Hudrisier
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Abstract

In addition to their well-known function as antibody-producing cells, B lymphocytes can markedly influence the course of infectious or noninfectious diseases via antibody-independent mechanisms. In tuberculosis (TB), B cells accumulate in lungs, yet their functional contribution to the host response remains poorly understood.

Journal details

Journal American Journal of Respiratory and Critical Care Medicine
Volume 197
Issue number 6
Pages 801-813
Available online
Publication date

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Publisher website (DOI) 10.1164/rccm.201707-1475OC
Europe PubMed Central 29161093
Pubmed 29161093

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