Corticosteroid-modulated immune activation in the tuberculosis immune reconstitution inflammatory syndrome

More about Open Access at the Crick

Authors list

Graeme Meintjes Keira H Skolimowska Katalin Wilkinson Kerryn Matthews Rebecca Tadokera Anali Conesa-Botella Ronnett Seldon Molebogeng X Rangaka Kevin Rebe Dominique J Pepper Chelsea Morroni Robert Colebunders Gary Maartens Robert Wilkinson
Scroll for detail on labs, facilities & authors

Abstract

HIV-tuberculosis-associated immune reconstitution inflammatory syndrome (TB-IRIS) is an immunopathological reaction to mycobacterial antigens induced by antiretroviral therapy. Prednisone reduces morbidity in TB-IRIS, but the mechanisms are unclear.

Journal details

Journal American Journal of Respiratory and Critical Care Medicine
Volume 186
Issue number 4
Pages 369-377
Publication date

Full text links

Publisher website (DOI) 10.1164/rccm.201201-0094OC
Europe PubMed Central 22700860
Pubmed 22700860

Keywords

Type of publication