Corticosteroid therapy, vitamin D status, and inflammatory cytokine profile in the HIV-TB immune reconstitution inflammatory syndrome (TB-IRIS)

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Tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) in patients coinfected with human immunodeficiency virus (HIV) and tuberculosis starting antiretroviral therapy (ART) is associated with hypercytokinemia. As adjunctive corticosteroid therapy and vitamin D have immunomodulatory properties, we investigated the relationship between cytokine/chemokine profiles, corticosteroid use, and vitamin D deficiency in TB-IRIS patients.

Journal details

Volume 55
Issue number 7
Pages 1004-1011
Publication date