Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy

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Globally there are approximately 9 million new active tuberculosis cases and 1.4 million deaths annually. Effective antituberculosis treatment monitoring is difficult as there are no existing biomarkers of poor adherence or inadequate treatment earlier than 2 months after treatment initiation. Inadequate treatment leads to worsening disease, disease transmission and drug resistance.

Journal details

Journal PLOS ONE
Volume 7
Issue number 10
Pages e46191
Publication date