Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution
Authors list
Rosalie Fisher Stuart Horswell Andrew Rowan Maximilian P Salm Elza C de Bruin Sakshi Gulati Nicholas McGranahan Mark Stares Marco Gerlinger Ignacio Varela Andrew Crockford Francesco Favero Virginie Quidville Fabrice André Carolina Navas Eva Gronroos David Nicol Steve Hazell David Hrouda Tim O'Brien Nik Matthews Ben Phillimore Sharmin Begum Adam Rabinowitz Jennifer Biggs Paul Bates Neil McDonald Gordon Stamp Bradley Spencer-Dene James J Hsieh Jianing Xu Lisa Pickering Martin Gore James Larkin Charles Swanton Toggle all authors (35)
Abstract
Genomic analysis of multi-focal renal cell carcinomas from an individual with a germline VHL mutation offers a unique opportunity to study tumor evolution.
Full text links
Publisher website (DOI) 10.1186/s13059-014-0433-z
Europe PubMed Central 25159823
Pubmed 25159823
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