Effect of prednisolone on inflammatory markers in pericardial tuberculosis: A pilot studyMore about Open Access at the Crick
Authors listJ Shenje Rachel Lai IL Ross BM Mayosi Robert Wilkinson M Ntsekhe Katalin Wilkinson
Pericardial disorders are a common cause of heart disease, and the most common cause of pericarditis in developing countries is tuberculous (TB) pericarditis. It has been shown that prednisolone added to standard anti-TB therapy leads to a lower rate of constrictive pericarditis. We conducted a pilot study to evaluate the effect of adjunctive prednisolone treatment on the concentration of inflammatory markers in pericardial tuberculosis, in order to inform immunological mechanisms at the disease site.