Genomic targets of Brachyury (T) in differentiating mouse embryonic stem cells

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Amanda L Evans Tiago Faial Michael J Gilchrist Thomas Down Ludovic Vallier Roger A Pedersen Fiona C Wardle Jim Smith
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Abstract

The T-box transcription factor Brachyury (T) is essential for formation of the posterior mesoderm and the notochord in vertebrate embryos. Work in the frog and the zebrafish has identified some direct genomic targets of Brachyury, but little is known about Brachyury targets in the mouse.

Journal details

Journal PLOS ONE
Volume 7
Issue number 3
Pages e33346
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Europe PubMed Central 22479388
Pubmed 22479388

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Crick labs/facilities

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