Neoadjuvant chemotherapy modulates the immune microenvironment in metastases of tubo-ovarian high-grade serous carcinoma
Authors listSteffen Böhm Anne Montfort Oliver MT Pearce Joanne Topping Probir Chakravarty Gemma LA Everitt Andrew Clear Jackie R McDermott Darren Ennis Thomas Dowe Amanda Fitzpatrick Elly C Brockbank Alexandra C Lawrence Arjun Jeyarajah Asma Z Faruqi Iain A McNeish Naveena Singh Michelle Lockley Frances R Balkwill
The purpose of this study was to assess the effect of neoadjuvant chemotherapy (NACT) on immune activation in stage IIIC/IV tubo-ovarian high-grade serous carcinoma (HGSC), and its relationship to treatment response.
Journal Clinical cancer research
Issue number 12