Prednisone for the prevention of paradoxical tuberculosis-associated IRIS

Authors list

Graeme Meintjes Cari Stek Lisette Blumenthal Friedrich Thienemann Charlotte Schutz Jozefien Buyze Raffaella Ravinetto Harry van Loen Amy Nair Amanda Jackson Robert Colebunders Gary Maartens Robert Wilkinson Lutgarde Lynen PredART Trial Team
Scroll for detail on labs, facilities & authors

Abstract

Early initiation of antiretroviral therapy (ART) in human immunodeficiency virus (HIV)-infected patients who have tuberculosis reduces mortality among patients with low CD4 counts, but it increases the risk of paradoxical tuberculosis-associated immune reconstitution inflammatory syndrome (IRIS).

Journal details

Journal New England Journal of Medicine
Volume 379
Issue number 20
Pages 1915-1925
Available online
Publication date

Full text links

Publisher website (DOI) 10.1056/NEJMoa1800762
Europe PubMed Central 30428290
Pubmed 30428290

Keywords

Related topics
Type of publication

Crick labs/facilities

Crick authors

Crick First author
Crick Corresponding author

Related content