Our mission is to pursue scientific research without boundaries. We aim for our research to be open, accessible and reproducible.
We publish the new ideas, knowledge and techniques that emerge from Crick research as peer-reviewed papers.
All of our primary research is open access, meaning it can be accessed free online.
We believe that freely accessible research is good for science. It removes barriers to accessing and analysing research and data, so research can be built upon and reaches the widest possible audience.
This is a full-time, fixed term (4 years) position on Crick terms and conditions of employment.
The research group
We are a highly interactive, international group of postdoctoral scientists, clinical and non-clinical PhD students leading research into cancer metabolism. We look forward to welcoming new members who share our passion to understand cancer metabolism and to identify vulnerabilities in these pathways as targets for therapy.
Our lab has made major contributions to understanding how nutrient availability, metabolism and ROS regulation impact cancer initiation and progression. We have recently been awarded an ERC grant to study the metabolic mechanisms underpinning obesity-driven pancreatic cancer by defining the metabolic crosstalk between the adipocytes in the tumour environment and the tumour cells themselves. Using metabolomic profiling, isotope tracing analysis and mouse models, the project aims to understand how adipocytes, the modulation of oxidative stress and formate metabolism affect adipocyte-cancer interactions. For this project we are seeking postdoctoral fellows who will make use of a wide range of techniques, including metabolomics, cell biology and mouse studies. We need dedicated, ambitious, creative and collaborative scientists with previous experience in cancer cell biology, mouse models of obesity or pancreas cancer and cancer cell or systemic metabolism. Postdoctoral Training Fellows are expected to be self-motivated and independently drive this own research projects, while also contributing to other projects on a collaborative basis (both in the lab and with external collaborators) and guide PhD students in their research.
Key experience and competencies
The post holder should embody and demonstrate our core Crick values: bold, imaginative, open, dynamic and collegial, in addition to the following:
PhD in the area of cancer biology or metabolism or in the final stages of PhD submission
High degree of proficiency in at least one of the following areas
Metabolic pathways – expertise in lipid metabolism is a bonus
Systemic metabolism in mice
Cancer models and the analysis of tumour/host interactions
Technical metabolomic analysis
Expertise in cell and molecular biology
Track record of writing papers as evidenced by publications or submitted manuscripts in refereed journals
Evidence of data presentation at scientific meetings
Experience of experimental design
Ability to work independently and also capable of interacting within a group
https://crick.wd3.myworkdayjobs.com/External/job/London/Postdoctoral-Training-Fellow_R421 36 2 Karen Vousden Karen Vousden Vousden K |Research Group - 2 (Karen Vousden) Karen Vousden Eleanor.Cowan@crick.ac.uk R421 Search engines may index Yes Science 4 <p>Competitive with benefits, subject to skills and experience.</p>